Nicotinamide Riboside (NR) IV Therapy in Las Vegas
 

What Is Nicotinamide Riboside (NR)?
NR IV therapy delivers nicotinamide riboside directly into the bloodstream, with 100% percent absorbtion. 
Nicotinamide riboside (NR) has recently become one of the most studied nicotinamide adenine dinucleotide (NAD+) precursors, due to its numerous potential health benefits mediated via elevated NAD+ content in the body. NAD+ is an essential coenzyme that plays important roles in various metabolic pathways and increasing its overall content has been confirmed as a valuable strategy for treating a wide variety of pathophysiological conditions.

Accumulating evidence on NRs’ health benefits has validated its efficiency across numerous animal and human studies for the treatment of a number of cardiovascular, neurodegenerative, and metabolic disorders. As the prevalence and morbidity of these conditions increases in modern society, the great necessity has arisen for a rapid translation of NR to therapeutic use and further establishment of its availability as a nutritional supplement. Here, we summarize currently available data on NR effects on metabolism, and several neurodegenerative and cardiovascular disorders, through to its application as a treatment for specific pathophysiological conditions. In addition, we have reviewed newly published research on the application of NR as a potential therapy against infections with several pathogens, including SARS-CoV-2. Additionally, to support rapid NR translation to therapeutics, the challenges related to its bioavailability and safety are addressed, together with the advantages of NR to other NAD+ precursors.


Once administered:

• NR enters cells efficiently

• It is converted into NAD⁺ intracellularly

• NAD⁺ is then available to support normal cellular metabolic functions

This pathway allows the body to regulate NAD⁺ production internally, rather than delivering NAD⁺ directly.


Why NR Is Offered in IV Form
 
While NR is commonly taken orally, intravenous administration offers several practical advantages in a clinical setting:

• Direct delivery without digestive breakdown

• Predictable dosing under medical supervision

• Shorter infusion times compared to NAD⁺ IV

• Generally well tolerated by patients

NR IV therapy is often selected by individuals seeking cellular and mitochondrial support without the prolonged infusion times associated with traditional NAD⁺ IV therapy.

• Cellular repair and recovery

• Improved mitochondrial ATP production

• Reduced oxidative stress and inflammation

• Enhanced vascular responsiveness and microcirculation

• Neurologic, muscular, and metabolic tissue health

By optimizing the cellular environment, NAD⁺ IV therapy helps the body’s natural healing and recovery processes function at a higher level—particularly in aging tissue, post-inflammatory states, neurologic stress, and high-performance demands.

Benefits of NR IV Therapy

• Supports intracellular NAD⁺ synthesis via established salvage pathways

• Facilitates mitochondrial oxidative metabolism and ATP generation

• Provides a precursor-based approach to NAD⁺ repletion rather than direct coenzyme delivery

• Allows for shorter infusion duration compared with NAD⁺ IV therapy

• Demonstrates favorable tolerability in clinical use

• Enables controlled dosing and administration under licensed medical supervision

• Bypasses gastrointestinal absorption variability associated with oral NR supplementation

• Supports enzymatic processes involved in cellular stress response and maintenance

Treatment Duration

• NR IV therapy is typically administered more quickly than traditional NAD⁺ infusions.

• Faster infusion rates are generally associated with fewer infusion-related discomforts.

• Lower incidence of chest pressure, flushing, or nausea compared to slower NAD⁺ infusions.

• Shorter infusion durations reduce interruptions and variability during administration.

​